During the penultimate interglacial period (~130 – 120 kyr BP), sea level was up to 6 m higher than present under enhanced boreal summer insolation, indicating a greatly diminished Greenland and/or Antarctic Ice Sheet. To better understand the sources of this sea level highstand, we will present new geochemical and sedimentological data from ocean core MD99-2227 located on the Eirik Drift that constrain the aerial extent of the southern Greenland Ice Sheet during the last two deglaciations and subsequent interglacials. Percent silt records from MD99-2227 indicate an ~25 kyr period of terrestrial sediment input to the Eirik Drift during the penultimate deglaciation and subsequent interglacial compared to only ~5 kyr of enhanced silt input during the last deglaciation and subsequent Holocene. This record suggests a greatly diminished southern Greenland Ice Sheet during the penultimate interglacial relative to present. The grain size data are in agreement with earlier Ti, Fe and magnetic grain size records from Eirik Drift and confirm that these proxies are recording changes in fine-grain sediment input rather than ice rafting or variability in Western Boundary Under Current strength. Nd-isotopic analyses of the silt fraction will allow identification of the source or sources of the silt size fraction, and initial results will be presented. In particular, these data will allow us to estimate the actual aerial extent and ice volume of the southern Greenland Ice Sheet, and thus its contribution to the penultimate interglacial sea level highstand.